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Finasteride blocks the conversion of testosterone to dihydrotestosterone, a hormone active mostly in the prostate and the scalp, and that all prostate cancers need to grow.
For example, the use of a protease inhibitor in combination with a reverse transcriptase inhibitor, which blocks the conversion of retroviral RNA into DNA, suppresses HIV replication better than either drug alone.
They were not suppressed by indomethacin (INDO), which blocks the conversion of DHDOC into THDOC.
Abiraterone acetate (AA) is a rationally designed CYP17 inhibitor that blocks the conversion of androgens from non-gonadal precursors effectively, thus reducing testosterone to undetectable levels.
The standard prophylactic and treatment regimen for hyperuricemia in patients with hematological malignancies previously included vigorous hydration, urinary alkalinization, and a xanthine oxidase inhibitor, allopurinol, which blocks the conversion of hypoxanthine and xanthine to uric acid.
MPA blocks the conversion of inosine monophosphate (IMP) to guanine monophosphate (GMP) affecting viral replication.
Similar(42)
In Seville and some other Spanish cities, groups of local activists have succeeded in blocking the conversion of historic buildings into luxury hotels.
For instance, in Indonesia, where habitat loss threatens the few remaining populations of orangutans, money has been earmarked to block the conversion of forests to commercial oil palm and rubber plantations.
Washington has done all it can without breaching World Trade Organisation rules to prevent its fracking boom from driving down the world price of gas by blocking the conversion of terminals designed to import the stuff into terminals that can export it.
Vitamin C, an antioxidant found in citrus fruits and many vegetables, may lower risks for cancer of the esophagus and stomach by neutralising cancer-causing chemicals formed in the body and blocking the conversion of nitrates to carcinogenic nitrosamines in the stomach.
DHA may block the conversion of MPTP to MPP+ or prevents the uptake of MPP+ into dopaminergic terminals.
More suggestions(17)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com