Amantadine blocks the action of glutamate, which is thought to be implicated in HD toxicity.
Mifepristone blocks the action of progesterone, a hormone necessary to sustain pregnancy.
But rather than stop production of testosterone, as some other drugs do, MDV3100 blocks the action of the hormone.
Diabetes mellitus appears in 20 to 40 percent of acromegalic subjects because excess growth hormone blocks the action of insulin.
The new drug, called REGN727, is a monoclonal antibody, made in a laboratory, that blocks the action of that protein.
All that for an article published today in the journal Cell suggesting that resveratrol blocks the action of a muscle enzyme called phosphodiesterase 4 in mice.
First, in a doctor's office, a woman takes three pills of mifepristone, which blocks the action of progesterone, a hormone required to maintain a pregnancy.
Denosumab is a monoclonal antibody that blocks the action of RANK ligand, a protein that plays a fundamental role in how bones are continuously broken down and rebuilt.
The most promising is PLX4032, a molecule which blocks the action of the protein produced by a specific mutation of a gene called B-RAF.
