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But the requirement for partnerships to pass through their money blocks the accumulation of earnings.
In contrast, the autophagy-inducing compound niclosamide blocks the accumulation of ubiquitinated proteins during proteasome inhibition.
Inhibition of actin polymerization blocks the accumulation of receptors CD2 and 2B4 at NK cell immune synapses, and the recruitment of 2B4 to detergent-resistant membrane domains [15], [26].
Engagement of ITIM-containing inhibitory receptors blocks the accumulation of F-actin at T cell and NK cell immune synapses [10] [12], and prevents the actin-dependent accumulation of glycosphingolipid-enriched domains at inhibitory synapses in YTS cells [13] and NK clones [9], [14].
Inhibition of protein synthesis blocks the accumulation of unfolded/misfolded proteins in ER and therefore can potentially alleviate ER stress-induced cell death.
Treatment of cells with cycloheximide to inhibit protein synthesis blocks the accumulation of sVEGFR1 in the medium but has no significant effect on VEGFR1-NTC (Fig 3C).
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When the scientists from Elan Pharmaceuticals in San Francisco gave mice the vaccine, the animals produced antibodies that blocked the accumulation of beta amyloid in their brains, and it even seemed to help clean up some that had already accumulated.
Moreover, antibody against the tight junction protein JAM-A and adhesion molecule ALCAM was able to block the accumulation of CD14 + CD16+ monocytes [38].
Previously, increased O-GlcNAcylation of tau has been shown to block the accumulation of tau aggregates within a tauopathy mouse model.
These findings demonstrated that the three M-specific siRNAs were able to specifically and effectively inhibit M glycoprotein expression in cultured cells by blocking the accumulation of mRNA, which provides an approach for studies on the functions of M protein and for the development of novel prophylactic or therapeutic agents for SCoV infection.
Our findings demonstrated that the S-specific siRNAs used in this study were able to specifically and effectively inhibit SARS-CoV S glycoprotein expression in cultured cells through blocking the accumulation of S mRNA, which may provide an approach for studies on the functions of SARS-CoV S gene and development of novel prophylactic or therapeutic agents for SARS-CoV.
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