Sentence examples for blocks membrane from inspiring English sources

Neuronal SCOP/PHLPP1 blocks membrane localized K-Ras (a small GTPase), which in turn inhibits the downstream kinase, mitogen activated protein kinase (MEK 3.

CtrIncA blocks membrane fusion whether present in v-SNARE (∼70% inhibition) or in t-SNARE (∼37% inhibition) liposomes (Fig. 1B and 1C).

To differentiate between those alternatives and identify the point of arrest in the viral life cycle induced by JMN3-003, we first examined whether the compound blocks membrane fusion and thus viral entry.

Further in vitro invasion assay using BEAS-2B and NIH3T3 cells stably transfected with overexpression constructs for full length wild-type AQP5 (and5) and its two mutants, N185D which blocks membrane trafficking and S156A which blocks phosphorylation on Ser156, showed that AQP5 induced cell invasions while both mutants did not.

Also, we analyzed the effect of Y-27632, a ROCK-I inhibitor that blocks membrane blebbing.

Thus, the Env will be arrested at an intermediate stage of its conformational transition, which also blocks membrane fusion and infection of the virus.

Nevertheless, only two out of the nine failed blocks membranes were not placed.

Aguilar-Carreno describes blocking membrane fusion as his research holy grail, and his lab is working to uncover more viral and cellular proteins that can play a key role.

Introducing substances into the postsynaptic cell that block membrane fusion at a number of different steps reduced LTP.

S9 also inhibited PI3K activity and block membrane ruffling in Rh30 cells (Fig S2).

An obvious host machinery to target in order to block membrane fusion is the SNARE machinery.