Sentence examples for blocks its interaction with from inspiring English sources
FRK-mediated phosphorylation of PTEN blocks its interaction with an E3 ubiquitin ligase and stabilizes PTEN protein.
Adalimumab binds specifically to TNF-alpha and blocks its interaction with cell surface TNF receptors.
This means that ERK phosphorylation of capicúa blocks its interaction with KPNA3.
BMS-936557 binds to IP-10 with high affinity (∼1 nM) and specifically blocks its interaction with CXCR3.
Kallen et al (1999) showed that lovastatin binds to the I-domain of LFA-1 and blocks its interaction with ICAM-1.
In resting cells, ASK1 forms an inactive complex together with the redox-sensitive protein thioredoxin, which blocks its interaction with TRAF2.
Indeed, it has been shown that Brm interacts with Cyclin E, that Mel-18, a human homologue of Posterior Sex Combs, interacts with Cyclin D2 possibly blocking its interaction with Cdks [56], [57] and we show here that the ETP Corto interacts with CycG.
Interestingly, Δ300 460 mutant retained the ability to bind SPOP, analogous to TRIM28, which inhibits TRIM24 ubiquitination without blocking its interaction with SPOP (Fig. 3h).
The VEGF pathway is inhibited by soluble VEGF receptors (soluble fetal liver kinase-1 [sFlk-1]) that bind VEGF and block its interaction with endothelial cells.
In this study, we describe the discovery of a novel series of inhibitors that targets HIV-1 NC protein by blocking its interaction with nucleic acids.
