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Water extinguishes fires by blocking the uptake of oxygen from the air.
For example, some antidepressant drugs work by blocking the uptake of norepinephrine or serotonin by nerve terminals.
Cocaine elevates dopamine (DA) in the nucleus accumbens (NAc) by blocking the uptake of DA through the DA transporter (DAT).
Several antidepressants, including Prozac, are thought to work by blocking the uptake of serotonin into nerve cells.
Methylphenidate (MPH), a psychoactive agent that acts mainly by blocking the uptake of dopamine, is the main drug used to treat Attention Deficit Hyperactivity Disorder in children and adolescents.
Our data suggests that methionine might exert a chemoprotective effect on B[a]P DNA adduct formation by attenuating intracellular GSH levels, blocking the uptake of B[a]P into cells, or by altering expression of proteins involved in DNA adduct formation.
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If you can block the uptake of fat by the pancreas, you can reverse the disease," he said.
ZN004 has been shown to block the uptake of fluorescently labeled F3 peptide by inhibiting internalization of nucleolin [13].
To block the uptake of free radioactive iodide in the thyroid, each subject received 300 mg of potassium iodide in the 24 h before the SPECT imaging.
Haloperidol and the unlabelled SIG343/SIG353 were able to block the uptake of the radiotracers in organs of high concentrations of σ receptors in naïve animals (data not shown), especially in the case of 18F-SIG343.
Furthermore, pre-administration of unlabeled HMS011 successfully blocked the uptake of radioactivity in a dose-dependent manner, supporting the specific binding of [11C]HMS011 in the rat and monkey brains.
More suggestions(20)
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