Sentence examples for blocking the transition of from inspiring English sources

Mutagenesis of Glu310 to Gln resulted in an inactive transporter, suggesting that Glu310 is involved in H+ binding/translocation, by blocking the transition of the transporter between the inward- and outward-open states (Doki et al. 2013).

Id1 is expressed in ESCs and can block the transition of ESCs to differentiation-primed epiblast (Ying et al., 2003; Pollard et al., 2006; Zhang et al., 2010).

A clue to their identity comes from the finding that inhibitor of DNA binding/differentiation (Id) proteins are able to block the transition of ESCs to epiblast stem cells (EpiSC) (Zhang et al., 2010).

A dose of 150 mg/kg body weight blocked the transition of cells from G1 through S for a 24 h interval when cell kinetics were measured by 3H-TdR autoradiography.

In rat hepatocytes, temperatures of 16 20°C blocked the transition from early to late endosomes, and from late endosomes to lysosomes [ 26, 27].

Prohibitin is an important antiproliferative protein inhibiting cell proliferation by blocking the G1/S transition of the cell cycle.

These data indicate that galangin is non-toxic and that it blocks the transition of Hs578T cells from the G0/G1 to the S phase of cell growth.

To test whether there is a functional link between both events, we blocked the G2/M transition of freshly isolated keratinocytes from human skin and monitored the effect on terminal differentiation and DNA replication.

We hypothesized that rapamycin may block the essential transition of KSHV from latency to lytic replication since low-level entrance into this second phase of the viral lifecycle is essential for survival of the virus in vivo and in vitro [3], [4].

Continuous polymerization of the PS blocks induced the transition of spherical micelles into other morphologies.

Thus, loss of Lsd1 culminates in a differentiation block at the transition of immature Gr1dim Mac1+ to mature Gr1high Mac1+ granulocytes.