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IL-10 increases the synthesis of miR-187, which promotes the termination of inflammation by blocking the transcripts of TNF- α and IL-12 [ 102].
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Poly-adenylation events cause a reduction in the transcript size, blocking the transcription of portions of its 3' region, together with the most 3' restriction site of the enzyme used for constructing the SAGE library.
It is possible in these cases they modulate gene expression by cleaving transcripts, physically interfering with transcription (an echo of the action of eukaryotic PIWI proteins), or blocking the release of transcripts from the template DNA [ 3, 57].
The judge blocked release of the transcript of the deposition's second day, but the plaintiffs' lawyers said they continued to pursue questions concerning the cardinal's supervision of priests in the archdiocese and the busted settlement in the case.
They block the translation of transcripts by binding to their complementary sequences in 3′ untranslated region (3′-UTR) regions of mRNAs (Berezikov et al., 2006).
Lawyers for the five men had sought to block the disclosure of the transcripts.
You can see the transcripts of their testimonies here.
In vitro studies found that pretreatment of chondrocytes with ASU blocked the activation of COX-2 transcripts and secretion of prostaglandin E2 (PGE2) to baseline levels after activation with lipopolysaccharide (LPS).
MicroRNAs (miRNAs) are small regulatory RNAs that act by blocking the translation and increasing the degradation of target transcripts.
Interestingly, we observed the same result when the C1845-infected cells were treated with the MEK inhibitor, U0126 whereas the PI3K inhibitor partially blocked the production of the VEGF transcript in wild type C1845-infected cells.
Both morpholinos efficiently block the translation of the neurod1 transcript as they completely prevent the expression of GFP from the Tg neurod1:egfp) transgenic line [ 40], while they do not disturb the overall morphology of the embryos [see Additional file 3: Figure S3].
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