Sentence examples for blocking the spreading of from inspiring English sources

Therefore, we suggest that these zinc finger DNA binding proteins are likely to play essential roles in blocking the spreading of DNA methylation and protecting the U-CGIs from being methylated.

This observation suggests that the accumulation of RNAPII molecules itself at the Tsix 3'-end could be involved in blocking the spreading of H3K27me3 from the hotspot to within Xist/ Tsix.

Immersion of wax-printed paper in water during autoclaving at 120°C blocked the spreading of wax, and the 96-zone pattern was preserved.

Our results suggest a possible mechanism that certain putative zinc finger protein binding sites over-represented in the boundary regions of the methylation-resistant CpG islands may block the spreading of methylation into these islands, and those TFBSs over-represented within the islands may both reinforce the methylation blocking and promote transcription.

One hypothesis of how Tsix might block the spreading of H3K27me3 is related to the chromatin remodelling activities that Tsix displays at the Xist locus.

Furthermore, we found that Dot1 does not simply act as a barrier to block the spreading of heterochromatin, but actively derepresses silent chromatin from a distal position.

We describe here that developmentally regulated transcription of Tsix, a crucial non-coding antisense to Xist, is required to block the spreading of the H3K27me3 domain to the adjacent H3K4me2-rich Xist region.

He expressed deep antipathy toward American foreign policy, saying it was blocking the spread of democracy in the Muslim world, not aiding it.

Maybe it will even have the courage to confront the inconvenient truths that Clarkson, Hammond and May ridiculed: that the world is running out of fossil fuels to burn, the petrol lobby is blocking the spread of electric cars and Formula One is a filthy sport that celebrates machismo and greed.

Future studies in animal models may allow broader conclusions regarding the physiological relevance of these specific antibody responses to blocking the spread of infective virus.

Hence, we speculate here that yet unknown activities associated with the RNAPII complex transcribing Tsix are directly responsible for blocking the spread of H3K27me3.