Sentence examples for blocking the influx of from inspiring English sources
Local anesthetics are able to induce pain relief since they bind to the sodium channel of excitable membranes, blocking the influx of sodium ions and the propagation of the nervous impulse.
Of note, CAT is an inhibitory peptide controlling catecholamine release from chromaffin cells and noradrenergic neurons by an autocrine regulatory mechanism, non-competitively blocking the influx of Ca2+ coupled to activation of the nicotinic acetylcholine receptor, as illustrated in Figure 9, but not when triggered by membrane depolarization [32].
Blocking the influx of Ca2+ protected the cells from oxidative insults.
Next, we wondered whether cell death of erythrocytes can be prevented by blocking the influx of Ca2+ and activation of sphingomyelinase.
Results in Figures 3 and 4 show that preincubation with F1 significantly decreased the Emax of the CaCl2-induced contractions in both media, suggesting that the vasodilatory effect of F1 is caused by blocking the influx of Ca2+ via VDCC and ROCC.
Following consumption the toxins bind with a high affinity to site 1 of the voltage-dependent sodium channel α-subunit of muscle and nerve cells, blocking the influx of sodium and preventing the generation and propagation of action potentials in these excitable cells (Cestele and Catterall 2000).
These findings are consistent with an earlier report in which PM014 blocked the influx of inflammatory cells and decreased pro-inflammatory cytokines, such as TNF-α and IL-6, in a murine model of COPD12.
Of these, 5 had a very strong effect, and were able to reduce the flow by up to 80%, while the substitution of one amino acid in particular – an asparagine located at position 447 in the protein – was able to block the influx of calcium ions completely.
Like the start-assistance from 2002, the main ambition was to block the influx of refugees and promote labor market participation among refugees and immigrants; formally, it targeted anyone who has not lived in the Kingdom of Denmark (including Greenland and the Faroe Islands) for at least seven of the last 8 years.
M2 ion channel blockers bind to the interior of the ion channel, block the influx of protons, and prevent hemagglutinin-mediated membrane fusion.
To test whether PRL secretion occurs via the L-type Ca2+ channel mechanism, we administered nifedipine to block the influx of Ca2+.
