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Squalene also exerted an antioxidant effect against isoproterenol-induced myocardial infarction by blocking the induction of lipid peroxidation.
We found that it can prevent CIE-induced up-regulation of NR2B gene expression through blocking the induction of demethylation.
Thus, IL-21 may block IL-7 action by preventing the phosphorylation of STAT5, thereby blocking the induction of Bcl-2.
We have previously shown that fucoidans from L. saccharina interfere with L- and P-selectins, thus promoting a decrease in PMN transmigration to the abdominal cavity and blocking the induction of acute peritonitis [16].
MUC1-C is involved in diverse signaling pathways that have been linked to tumorigenesis, functioning either in promoting cell proliferation or blocking the induction of apoptosis [38], [39], [40], [41], [42].
One of the regulators of this pathway is Dkk1, which antagonizes Wnt signalling through the formation of a ternary complex with the transmembrane receptors Krm1/2 and Lrp5/6, thereby blocking the induction of Wnt signalling by the latter ones.
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N-acetyl-cysteine, a glutathione precursor, blocked the induction of apoptosis by doxorubicin plus sulforaphane.
Hence, parasite repression of DUSP1 could block the induction of arginase, a known mediator of killing of H. polygyrus in the mouse32.
In addition, pretreatment with CAPE or JSH-23 also blocked the induction of miR-200c-3p miR-200c-3p miR-200c-3poly (incellsPS or Ltreatedure 4f,h and j).
However, ethanol virtually blocked the induction of LTP in slices from immature animals.
Mutations in the NPR1 gene completely block the induction of SAR by signals such as salicylic acid (SA).
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