Sentence examples for blocking the generation of from inspiring English sources

Regulatory T cells could interact directly with DCs by downregulating their surface expression of CD80/CD86, thus reducing their antigen-presenting ability and blocking the generation of allergen-specific T cell responses.

It exerts anti-HIV activity by inhibiting the production of HIV-1 double-stranded viral DNA from a single-stranded DNA intermediate, rather than blocking the generation of single-stranded DNA from a RNA template, which is the mechanism of action of current HIV-1 RT inhibitors.

The proposed treatment attacks the OA process at its core, blocking the generation of chondrocytes with an autolytic phenotype.

SCEE may give cell protection by hindering CCl4-mediated lipid peroxidation, hence blocking the generation of free radical derivatives [ 49].

Blocking the generation of prostaglandins by celecoxib (Celebrex) prevented the increased secretion of NGF by tooth perfusates in rats after an inflammatory stress [ 56].

Taken together, this NR2F6-centered pathway identified may very well offer new targets that are aimed at blocking the generation of pathogenic Th17 cells for the treatment of autoimmune diseases.

Rubber particles can block the generation of cracks, leading to the improvement of low-temperature properties of the binder.

Interestingly, while Notch signals are required for LTi development, sustained Notch signals can block the generation of LTi cells (Chea et al., 2016).

In his 1967 paper, the moral that Chisholm drew from his argument was scepticism about transworld identity, based partly on scepticism about whether the non-trivial individual essences that would block the generation of role-switching worlds are available.

The supposition that Adam and Noah differ in their essential properties in this way, although sufficient to block the generation of this example of a role-switching world, does not by itself imply that each of Adam and Noah has an individual essence: a set of essential properties whose possession is (not only necessary but also) sufficient for being Adam or Noah.

In addition, TUTase has been shown to be involved in degrading the let-7 precursor (pre-let-7) to block the generation of mature let-7 in the cytoplasm (Hagan et al., 2009; Heo et al., 2009; Thornton et al., 2012).