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Consistently, blocking the function of miR-200c-3p miR-200c-3p miR-200c-3pmice from ALI, indicating miR-200c-3protectsotential therapeutic target.
They knew from previous research that blocking the function of COMPASS somehow extended the worms' lifespan by as much as 30percentt.
Among the different ways of blocking the function of this enzyme, inhibiting its ATPase activity has been relatively less investigated.
This partially reflects a historical bias, as molecularly targeted oncology drugs are typically inhibitors or antagonists that are aimed at blocking the function of oncoproteins, which are clustered into a single major oncogenic subnetwork.
This study suggests that the synthetic glycoprotein-based glyco-ligands can be useful for different applications, including blocking the function of galectin-3 in cancer metastasis.
In fact, the finding has raised the question of whether insomnia medications that work by blocking the function of the orexin receptor could harm the heart, although this has not yet been studied, Perez said.
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Furthermore, blocking the functions of this protein and associated pathway was able to reduce the inflammation to less harmful levels.
This may also provide an additional cell-biological explanation as to how blocking the functions of integrins can sensitize cancer cells to therapeutic modalities, including IR (see also below)13,14,15,16.
Recent studies have shown that nilotinib induces potent sensitization to anticancer agents by blocking the functions of ABCB1/P-glycoprotein (P-gp) in multidrug resistance (MDR).
Blocking the functions of TAMs inhibits tumorigenesis.
In addition, functionalized nanoparticles themselves or their metabolites can also block the function of ABC transporters such as P-gp by direct or indirect interaction and inhibition.
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