Sentence examples for blocking the binding from inspiring English sources

The protein also binds PDGF-B, blocking the binding to its receptors and the proliferation signaling [ 10].

Soluble Fas (sFas) can bind to membrane-bound FasL, thus blocking the binding of the ligand to the Fas receptor, preventing apoptosis induction in the target cell, and enhancing the immunosuppressive effects of tumors.

They exert their action by blocking the binding of AngII on the AT1 receptor.

Thus, we concluded that both compounds inhibit the sulfur transfer reaction from the persulfurated intermediate by blocking the binding of the sulfur acceptor to 3MST (Fig. 4c).

Indeed, a TPP analogue (pyrithiamine pyrophosphate, PTPP) shows antimicrobial activity by blocking the binding site of the TPP-sensing riboswitch, shutting down thiamine metabolism in bacteria.

Blocking the binding of VCAM to α4β1 is thought to be a way of controlling a number of disease processes.

The data suggested the potential role of P2 and P3 peptides in successfully blocking the binding of AAF-II EAEC with HEp-2 cell receptors.

Our results also indicate that the nitrogen-containing bisphosphonate drugs are potential inhibitors of FPPs and other trans-prenyltransferases aiming at blocking the binding of FPP.

Blocking the binding of TNF-α to TNF receptor subtype-1 (TNFR1) is an important strategy for the treatment of rheumatoid arthritis (RA).

It is thus likely that the repebody suppresses the hC5a-mediated immune response in monocytes by blocking the binding of hC5a to its receptor.

As can been seen from Fig. 7, preincubation with cRGD protected the cells against PDT, likely by blocking the binding by competitive inhibition of the construct with integrins and thus preventing receptor binding and cellular uptake.