Sentence examples for blocking the assembly of from inspiring English sources

PLpro-TM disrupts activation of the IRF3 pathway induced by STING-TRAF3-TBK1 blockinging the assembly of the complex, and it deubiquitinates the signaling molecules RIG-I, TRAF3, STING, TBK1, and IRF3.

Both scFV were incapable of blocking the assembly of VLP, or be copackaged with Pr55Gag into VLP.

(B ) The inhibitor, by binding and interfering with the TAF2 IDR, arrests TFIID isomerization and Pol II engagement, thus, blocking the assembly of a functional PIC.

As discussed by Kuwano et al. [ 33], NF90 appeared to reduce translation initiation by blocking the assembly of components of the translation initiation apparatus on a specific mRNA, although NF90 might also recruit one or several types of microRNAs onto the target mRNA, repressing translation via the RISC (RNA-induced silencing complex), as shown for HuR, another RBP [ 35].

Amantadine can also block the assembly of influenza virus during viral replication.

Neither dominant-negative variants nor peptide inhibitors of Rho GTPases blocked the assembly of the cytoplasmic actin network.

13 Inhibition activity of naringenin was observed which blocked the assembly of intracellular infectious viral molecules without interacting the intracellular levels of viral protein or RNA.

The ability of p16INK4a to inhibit the cyclin D-dependent kinases also enables it to block the assembly of DNA replication complexes onto chromatin and thus inhibit DNA replication, a function not shared by p21Waf1 [ 50].

MBP-1 can block the assembly of the basal transcription complex by competing with TBP, as reported for the c-MYC P2 promoter [ 7], or it may bind the promoter regulatory sequences and recruit HDAC1, as we suggest here, for the ERBB2 gene.

To block the assembly of mitochondrial respiratory complexes, we generated strains that lack mtDNA (rho) and examined the distribution of the two MICOS subcomplexes as marked by either Mic60 foci (in ∆MICOS + Mic60-EGFP cells) or Mic27 foci (in ∆ mic60 + Mic27-mCherry cells).

Cycloheximide should thus block the assembly, but not the disassembly, of the RPC.