Sentence examples for blocking the approach of from inspiring English sources

The tetrameric arrangement and the negative charge distribution close to the active sites of the enzyme, have suggested the design of complementary multifunctional receptors that might bind to the active region of the protein blocking the approach of the substrate.

The galeota, commanded by Ursúa, rowed east with 108 soldiers; half way across the lake it encountered a large fleet of canoes blocking the approach to Nojpetén – and simply rowed through them.

At Halidon Hill, Edward blocked the approach of a relief force under Sir Archibald Douglas, regent for David II.

The electrical double layers that are composed of stern and diffuse layers have a certain thickness, which can block the approach of the adsorption for the adsorbate to the adsorbents.

Onshore, the Al Qasimi and their Bedouin allies (whose numbers are unknown, but were significantly less than 20,000) formed a series of emplaced defences around the town that were protected from offshore bombardment by sandbanks which blocked the approach of Wainwright's heavier warships.

The condensed chromatin structure may block the approach of TALEN to the target site.

A hairdresser testified about the irate phone calls her salon received for continuing to tend to the hair care of Ms. Drew, and an interior designer detailed both how she sold Ms. Drew blinds to block the hostile approaches of neighbors, while being hectored herself for continuing to advertise her business in a coupon book distributed by Ms. Drew.

In contrast to the well-appreciated approach of blocking the overall output of various metabolic pathways as a potential therapeutic avenue, we demonstrate that additional vulnerabilities that rely on the accumulation of toxic intermediates can occur in specific cancer subsets.

On western urging, Riyadh had promised to move towards "intelligence-led interdiction", stopping and searching individual ships on which there was good reason to believe arms were being smuggled, and away from a blanket policy of blocking the majority of vessels approaching Yemeni ports.

If cancer cell ECM interactions could be limited by minimizing mesothelial cell retraction, the approach of blocking mesothelial cancer cell interactions would become more relevant.

He added that "hundreds of other drugs in development" are based on the same approach of blocking the activity of specific enzymes associated with a given type of cancer.