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Lin-4, they learned, works to keep development on track by aligning itself with important protein-coding RNAs and blocking production of the corresponding proteins.
Finally, the team is screening for drugs that prevent the CTGF gene from being turned on, thus blocking production of the factor.
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The best lycopene producer had 24 genetic changes four that completed blocked production of the gene's protein, and 20 that resulted in small or large changes in the expression of that gene.
Congress last year blocked production of the Bigeye, but the Reagan Administration asked again for $77.3 million in the Pentagon's 1987 budget, which is now under consideration by the legislature.
In the switch he and his colleagues built from DNA, two genes next to each other in a bacterial genome both produced proteins when they were "on". But Collins set things up so that each protein would block production of the other if gene 1 was on, it would keep gene 2 off, and vice versa.
Is this due to blocked production of the gene, or is it due to a mutation that prevents the resulting protein from working properly?
Evidence of Warner's eroding control at Warner Bros. included his failure to block production of the controversial but highly influential film, Bonnie and Clyde, a film project he initially "hated".
These results demonstrated that the MOs targeting hoxd10a and hoxd13a efficiently blocked production of the mature hoxd10a and hoxd13a spliced transcripts.
Because of this, the drugs do not block production of the early viral proteins Tat, Rev and Nef (Nath, 2002).
Firstly, compounds were tested for the ability to block production of a substrate product of the NS2 autoprotease in an in vitro assay.
Independent from us, Hougee et al. demonstrated in a mouse CIA model that orally administered apocynin restores the blocked production of cartilage proteoglycan in the arthritic joint [ 11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com