Sentence examples for blocking of cell cycle from inspiring English sources

OspA interferes with the response of lymphocytes to proliferative stimuli including a blocking of cell cycle phase progression.

Therefore, growth inhibition by BLU may result from the blocking of cell cycle entry.

HU (Sigma) was prepared as a 1 M stock solution in ddH2O and used for blocking of cell cycle, at a final concentration of 30 mM.

Our results showed that Sall2 enhanced the p16 minigene blocking of cell cycle progression and p16 knockdown with siRNA abolished most of the Sall2 inhibition of cell cycle progression.

By FACS analysis, various events, such as the blocking of cell cycle, activation of apoptotic genes or proteins, and loss of plasma membrane phospholipid asymmetry, can be detected and quantified to determine the apoptosis pathway [ 23].

By analyzing the cell cycle populations with transfected Sall2, p16 and co-transfection of Sall2 and p16, we found that knockdown of p16 expression abolished over half of the Sall2-induced cell cycle G2/M phase reduction; therefore, Sall2 regulation of p16 plays a major role in Sall2-induced blocking of cell cycle progression in addition to other Sall2 effects.

The over-expressed G4 includes p27 (12 of 33 Neural samples, P=0.159) and RBX1 (16 of 33 Neural samples, P=5.51 E−5), where p27 can block progression of cell cycle [ 38].

The compounds show a promising inhibitory growth efficacy (IC50 50–100 μM) in SNU449 cell line, as well as block of cell cycle progression and induction of apoptosis, and can be considered as lead compounds for further SAR developments.

Furthermore, the inhibition effect of liposomes on SW480 colon cancer cells was dramatic enhanced due to a block of cell cycle at G0/G1 phase, and CPL had a higher inhibition rate than bufalin liposomes (BFL) because of the anticancer effect of citrus pectin.

The loss of VRK1 results in a block of cell cycle progression in G1/S.

Treatment of LAN-5 with antagomir-17-5p causes not only a block of cell cycle, but also a dramatic apoptosis.