Sentence examples for blocking mAb has been from inspiring English sources

Furthermore, an anti-JAM-C blocking mAb has been shown to suppress the growth of glioma and Lewis lung carcinoma tumors in mice (18, 19).

To date, three immune-checkpoint-blocking mAbs have been approved in the USA for the treatment of patients with several types of cancer, and more patients will benefit from immunomodulatory mAb therapy in the months and years ahead.

This well characterized mAb has been extensively used to block CD40 engagement by CD40L expressing cells.

Anti-mouse Dll4 blocking mAb had no effect on osteoclast differentiation, consistent with no expression of Dll4 during osteoclastogenesis.

Other anti-CD22 mAb have been studied and have not generated significant responses in animal models or human clinical trials [ 11, 12] likely because they, like HB22.27 bind to a non-ligand blocking region of CD22.

Most of the reported mAbs has been focused on the neutralization of RBD to block the interaction of RBD to hDPP4 and extreme potency has been exhibited by mAbs targeting RBD.

Stimulating activity of the anti-receptor mAbs and blocking activity of the anti-ligand mAbs have been verified in vitro or in vivo [ 9, 13- 20].

Human, murine, and rat monoclonal antibodies (mAbs) have been derived that target epitopes I, IIb, III, and V5,24,25,26.

Various therapeutic approaches including monoclonal antibodies (mAbs) have been developed to block Her2 activity to combat tumor growth (Keler et al. 1997; Ben-Kasus et al. 2009; Vasconcellos et al. 2013).

Since many of these MAbs have been isolated in the last few years, the potency and breadth of MAb combinations have not been well characterized.

The variable (V) genes of TP-1 and TP-3 MAbs have been cloned and sequenced.