Sentence examples for blocking ligand as a from inspiring English sources

The negative control sequences are not enriched in either sample Similar results were obtained using the HaloCHIP blocking ligand as a control (data not shown).

AEAPTS acts as both a blocking ligand at Ni2+ and as a linker to tether the cyanometallate structure to the silica matrix during sol gel processing through reaction of the trialkoxysilyl groups.

Furthermore these antibodies induce downregulation of surface receptors in addition to blocking ligand binding to receptors as well as incite antibody-dependent cell-mediated cytotoxicity [ 38].

On the other hand, 5-amtz ligand exhibits two different coordination modes in compounds 3 and 4 as a result of the presence or absence of an additional blocking ligand.

47 The problem of a blocked ligand entry site by ECL2 (as in rhodopsin) should not arise in ORs, as their ECL2 loops are very long, and for most of the residues, there will not be any equivalences in the template.

BADGE was described as a PPARγ antagonist that blocked ligand-mediated adipocyte differentiation in 3T3-L1 and 3T3-F442 celinesnes (Wright et al. 2000).

As expected, HER2Mab effectively blocked ligand-independent and ligand-induced HER2/HER3 interactions in MCF7-HER2 cells (Fig. 4h and i). Figure 4j is the statistical analysis of images shown in Figure 4f i.

It does not block interactions of CD22 with its ligand, as do some anti-CD22 monoclonal antibodies, but it does initiate signaling through the CD22 molecule [ 9].

The VEGF pathway was identified as a target for antitumour therapy more than 15 years ago, and early studies showed that blocking the VEGF-A ligand with a monoclonal antibody could result in strong suppression of tumour growth (Ferrara, 1999).

Osteoprotegerin (OPG) is a soluble decoy receptor that acts as a receptor antagonist, blocking OPG ligand (OPGL) induced osteoclastogenesis.

7D12 sterically blocks ligand binding to EGFR in a manner similar to that of cetuximab.