Sentence examples for blocking its fusion with from inspiring English sources
These antibodies bind to the membrane-proximal stem of haemagglutinin, the major viral surface protein, and neutralize the influenza virus by blocking its fusion with the host cell [2].
(C) PLP2-TM activates autophagosome formation but blocks its fusion with lysosomes.
Since decreased LC3-II content could result from either impaired synthesis or enhanced degradation after lysosomal fusion, we assessed LC3-II synthesis by blocking its degradation with the lysosomal proton pump inhibitor Bafilomycin A1.
It then forms small pores in the phagosome, blocking the acidification of this compartment and thereby preventing its fusion with lysosomes (Singh et al., 2008).
VHMs are chemical substances that can destroy HIV, block its entry into or fusion with the target cell or inhibit HIV replication once the virus has entered a target cell.
The broad-spectrum antiviral arbidol (Arb) inhibits cell entry of enveloped viruses by blocking viral fusion with host cell membrane.
Inactivation of recycling endosomes, blocking endosome fusion with the plasma membrane, or downregulation of Rab11 GTPase that controls outbound trafficking of perinuclear recycling endosomes, all abrogate tTG secretion.
It has been identified that M2 proteins of influenza A virus play a critical role in blocking autophagosome fusion with lysosome.
Although the precise mechanism is unclear, it is likely that the bacterial proteins expressed on the surface of these infectious phagosomes are responsible for blocking fusion with the endocytic compartments [16], [17].
A potentially confounding factor could be the use of hydroxychloroquine, which might increase autophagosome count by blocking fusion with lysosomes, however there was no significant correlation between LC3-BDI and use of this drug (p=0.52).
