Sentence examples for blocking its association with from inspiring English sources

Another mode of inhibition of HDM2 is by blocking its association with the proteasome.

Interestingly, binding of Nedd9 to AurA protects AurA from degradation by blocking its association with the APC/C ubiquitin ligase complex.

Although this data could indicate that the addition of an HtS dual-tag on TRF1's N-terminus may block its association with other members of the complex, this may not be the case as the co-purification of endogenous TRF1 via HtS-TRF2 or PtS-POT1 was equally as low.

(PMID 10611223) Pim phosphorylation of Bad was also found to block its association with Bcl-XL.

Evi-1 was a zinc finger-containing and site specific DNA-binding transcription factor, but it did not seem to inhibit pu.1 binding to DNA, but rather to block its association with the co-activator JNK and its substrates [ 21].

And Taddei et al. report that simply moving the HXK1 gene, by blocking or encouraging its association with the nuclear periphery, significantly alters gene expression.

Little is known about the prevalence of bundle branch block (BBB) and its association with other cardiovascular disease (CVD) risk factors in the general population.

The MLL gene rearrangement blocks differentiation and its association with FLT3 supports this model as well.

To date, the lack of a clear understanding of the aetiology of nIIP remains one of the main stumbling blocks in establishing its association with HM.

In addition, this is the first study to examine the role of a possible community segregation variable, percentage of African American residents in a block group, and its association with knee OA.

Also known as Akt1s1, PRAS40 can block mTORC1 activity through its association with Raptor [ 17, 18].