Sentence examples for blocking formation of the from inspiring English sources
Knowledge of the mechanism of cancer initiation by estrogens suggests that prevention of cancer can be achieved by blocking formation of the depurinating estrogen-DNA adducts.
Acetaminophen inhibits prostaglandin hydrogen synthase by reducing the protoporphyrin radical cation and blocking formation of the catalytic tyrosyl radical [ 46, 47].
This peptide prevents viral entry into cells [ 42, 119], blocking formation of the 6-helix bundle required for fusion, by binding to HIV gp120 and cellular CD4 through interactions with their O- and N-linked sugars [ 120].
Crystal structures of Asf1 bound to the H3/H4 dimer show that Asf1 binds to H3 at the H3/H4 dimerization surface, physically blocking formation of the H3/H4 tetramer [ 23, 24].
Cytochrome c-induced caspase-9 activation is regulated at multiple levels, and tRNA was reported recently to bind to cytochrome c, blocking formation of the apoptosome and the subsequent activation of caspase-9.
The discovery of prozyme opens up new prospects for inhibiting AdoMetDC in trypanosomatids, either by blocking formation of the active AdoMetDC prozyme complex or by stabilizing the inactive conformation of AdoMetDC.
FMRP also recruits cytoplasmic FMRP-interacting protein (CYFIP1) to block formation of the eIF4F complex preventing translation initiation (Napoli et al., 2008).
This finding is consistent with the previous observation that disruption of the type IIb interface on Fas DD did not block formation of the Fas DD/FADD DD complex.
Thus, 5D10 specifically binds to DR6 within the CRD 3-4 domains to block formation of the DR6/p75NTR receptor complex, thereby preventing A β42-induced cell death in cultured neocortical neurons.
In parallel to its ability to block noradrenalin, vitamin E also blocked formation of gastric lesions in the rats exposed to stress.
