Sentence examples for blocking activity to a from inspiring English sources

Drug combinations with taxanes have been reported to increase cell killing, as compared with the effects of single agents, either by combining dual cell death promoting activities (Bijnsdorp et al, 2008; Reiner et al, 2009) or by adding a drug efflux blocking activity to a cytotoxic effect (Miettinen et al, 2009).

IgG4 only weakly responds to many antigens and possesses a blocking activity to IgG1- and IgE-mediated immune functions [ 15].

The electrophysiological experiments further indicated that the recombinant LmKTx10 peptide has an interesting pharmacological profile: it blocks Kv1.3 channel with IC50 = 28 nM which is moderate Kv1.3 channel blocking activity compared to the other a-KTxs toxins, and exhibits good selectivity on Kv1.3 over Kv1.1 and Kv1.2, about 60 folds and 450 folds, respectively.

The average transmission blocking activity increased to greater than 97% in all the animals after a booster dose.

They were first identified in Drosophila on the basis of their enhancer-promoter blocking activity, an activity thought to restrict the promiscuous activity of enhancers.

Mutations in this sequence compromise the blocking activity of a 4×pHS1 multimer, while multimerization of a 27-bp oligo spanning the Elba sequence (8×Elba) [see (D )] is sufficient to confer early blocking activity.

Even if the blocking activity does not lead to a melt event, the temperatures nevertheless show a warming tendency during those days.

These opposing (spreading and blocking) activities would come to a dynamical equilibrium under a given physiological condition of the cells to establish the observed genomic methylation patterns.

In preliminary studies with heat killed cells, blocking activity was relatively similar to that observed for live cells, except that heat inactivated control cells had an unexpectedly high level of inherent blocking activity.

Moreover, the principal alkaloid of Delphinium genus, methyllycaconitine (MLA), has been reported to have a blocking activity at alpha 7-type neuronal nicotinic receptor.

Our anti-SEC24A antibody also failed to exhibit blocking activity in the budding assay.