Sentence examples for blocking activation of the from inspiring English sources

Typical treatments for prostate cancer involve blocking activation of the androgen receptor by androgens.

This is achieved in part through blocking activation of the canonical Wnt/β-catenin signaling pathway.

Telomeres impede chromosomal fusion (end-to-end joining) by blocking activation of the DNA damage checkpoint response and locally impairing double-strand break repair.

In addition, capsules contribute to virulence by protecting bacteria from phagocytosis and possibly from serum killing, in part by blocking activation of the alternative complement pathway [ 23, 15].

VP35 is a cofactor in the RNA polymerase transcription complex, and helps the virus evade the immune response by blocking activation of the interferon regulatory factor 3, which is required for the induction of interferons alpha and beta.

We next determined whether ADI potentiated the GEM-induced apoptosis of PANC-1 cells by blocking activation of the NF-κB pathway.

Molecular studies showed that silk proteins suppressed the expression of Notch-activated genes and blocked activation of the Notch-specific reporter.

Knockdown of DDX41 expression blocked activation of the mitogen-activated protein kinase TBK1 (TANK-binding kinase 1) and the transcription factors NF-κB and IRF3 (interferon regulatory factor) by B-form DNA but not RNA.

Inhibition of FAK blocked activation of the identified matrix-mediated pathways, while independent inhibition of JNK nearly abolished phosphorylated-c-Jun (p-c-Jun) and attenuated the pathways identified to promote enamel regeneration.

In contrast, in bronchial epithelial cells, FHA blocked activation of the NF-κB pathway at all examined time points.

The φA-X-φB motif inserts into the docking groove on the MAP kinase, and alanine substitutions in this motif have been shown to block activation of the MEF2A transcription factor by the MAPK p38 in mammalian cells [15].