Sentence examples for blocker potency from inspiring English sources

(4) Uptake rates are positively correlated with releaser and MPH, but not blocker, potency.

Furthermore, the relationship between QA chain length and blocker potency for K2P channels showed greater similarity with Shaker than with Kir1.1.

In the presence of CsCl (non-selective K+ channel blocker), the relaxant potency of XF-OE was not altered, indicating a non-participation of these channels.

The blockers exhibit high potency against human vascular smooth muscle cell migration, in particular margatoxin which acts with an IC50 of 85 pM.

Phenethyl aminoheterocycles like compound 1 were known to be potent IKur blockers although they lacked potency in vivo.

While cell culture studies have suggested that increasing DAT levels reduces the potency of blockers, but not releasers, in vivo studies have shown that increasing DAT levels increases the potency of releasers, but not blockers, to inhibit dopamine uptake.

These two drugs were predicted to interact with β adrenergic receptor by SEA, and later experiments revealed that they are medium-potency blockers of β1 subtype (i.e., Ki = 4.4 μM for Prozac and 10 μM for Paxil).

Overall, our data can explain why channel blockers have lower potencies in ELIC than at either GLIC or Cys-loop receptors and show that using ELIC as a model for interactions with such compounds (for in silico and functional studies) is likely to be more accurate if their entry into the pore is permitted by substitutions of F16′.

A new ANO1 blocker, MONNA with much more potency has been developed and its effect as a cancer treatment is greatly anticipated 62. None declared.

In many of the transformations hERG inhibition follows the expected qualitative trends: decreasing lipophilicity, decreasing basicity, and increasing acidity all decrease the potency of hERG blockers.

The tricyclic antidepressant imipramine was a high-potency fascin-pathway blocker in our assay.