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The above results thus suggest that H141A HDAC-1 blocked the attenuated expression of cyclins D1 and A, resulting in cell cycle progression and cell proliferation.
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The decreased eNOS expression appears to be concomitant with the attenuated expression found for CSE and HO-1.
Our data show that atorvastatin decreases TLR4 expression/activation, a modulation that might have a role in the attenuated expression of inflammatory mediators in response to a septic insult.
The attenuated expression produced by the ZRS 3′ end deletion revealed an unexpected variability inherent in regulating digit number.
The attenuated expression of CD34 in TPX2 siRNA-treated tumors coincided with the overexpression of IGFBP-3.
We are the first to provide evidence to suggest that the attenuated expression of miR-184 in cancer is potentially a result of epigenetic mechanisms.
To investigate whether the attenuated expression of PPARγ and C/EBPα further affected the activation of their target gene, aP2, we investigated the expression of aP2 under the same conditions.
The truncated isoforms of some GPCRs play a pronounced role in associating with the detaining of the WT isoform in the endoplasmic reticulum (ER), which makes the attenuated expression of the WT isoform on the cell surface [ 28, 29].
Our data show that diacerhein decreases activation of the IKK/IκB/NF-κB pathway, a modulation that may play a role in the attenuated expression of inflammatory mediators in response to a septic insult.
This test involves using short strands of RNA to block the expression of specific genes.
Knockdown of HIF-1α using a shRNA plasmid blocked the hypoxic induction of KCNMB1 expression.
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