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Chemicals that block nicotine's binding to the receptor also blocked proliferation of the cells.
Cyclopamine treatment of murine medulloblastoma cells blocked proliferation in vitro and induced changes in gene expression consistent with initiation of neuronal differentiation and loss of neuronal stem cell-like character.
Replacement of the benzimidazole ring with a naphthyl group resulted in a 10 50-fold 10 50-foldgand potency, but these examplossdownregulated binmarkers of Pin1 activity and bligand potencyration of PC3 cells.
Vascular endothelial growth factor activation of the p44/p42 mitogen-activated protein kinase pathway, which is required for angiogenesis, was supported by adhesion through either α1β1, α2β1, αvβ3, or αvβ5, and pharmacologic inhibition of this pathway blocked proliferation and suppressed survival.
Overexpression of p21 in osteoblasts blocked proliferation and differentiation [42].
We show that the QKI isoforms blocked proliferation and promoted Schwann cell differentiation and myelination.
Similar(9)
American Presidents have long vowed to block proliferation of the world's deadliest weapon.
They promote rather than block proliferation by encouraging the country's neighbours to develop their own, comparable weapons.
Further evaluation in 3D organ-like multilayer aggregates showed that it could block proliferation at submicromolar level.
Expression of GMRα in these mutants was confirmed by blocking proliferation with GM-CSF antibodies, detection of high-affinity receptors, and Northern blot analysis.
Such secondary supplier-chains make tracking, let alone blocking, proliferation much more difficult.Careless friendsMeanwhile, export controls need tightening up all round.
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