Sentence examples for blocked pathway from inspiring English sources

Although satisfactory results were obtained in terms of initial response, many of these inhibitors were found to exhibit high toxicity, and rapid development of resistance was observed due to re-activation of the blocked pathway or activation of an alternative pro-survival pathway.

One reason lies in the distributed nature of metabolic systems, where several bypasses may exist around any blocked pathway.

Since such a capacitively blocked pathway cannot carry a faradaic dc current, it would not be visible in the O tracer incorporation experiments.

Repair the bathroom exhaust fan and its blocked pathway to the outdoors.

"Too much snow out there," said Mr. Huckabee, a former Arkansas governor, explaining his wariness of the slick roads and blocked pathways of New Hampshire.

Throughout the game, an evil artificial intelligence called SHODAN hinders the player's progress with traps and blocked pathways.

The blocked pathways already threatened to melt into a slushy fuck you in the afternoon sun, likely inspiring the generally polite-but-utilitarian pace and demeanor of the people I passed on my way up Mulberry Street.

As with other reconstructed metabolic networks, the continued existence of blocked pathways (Table 1) highlights that our knowledge of yeast metabolism is incomplete.

As Mre11 in the model is a subunit of the MRN complex, which solely activates ATM, the blocked pathways are the same as in the Ataxia telangiectasia simulation.

Many of these blocked reactions were concentrated within pathways that are almost entirely blocked, such as metabolism of terpenoids and polyketides--suggesting that many of the blocked reactions are actually a result of blocked pathways.

Look for blocked pathways to exits, fire extinguishers, water valves, gas valves.