Sentence examples for blockage of the interaction from inspiring English sources

Blockage of the interaction of CD2 with its ligand CD58 is expected to bring out potential therapeutic value for autoimmune diseases and organ transplantation.

We agree adding a control antibody to eliminate FcR binding would be an informative approach to determine if the mechanism is via blockage of the interaction of CD47 with SIRPa, however, as the reviewers have already described, Willingham and colleagues did not use this approach.

Blockage of the interactions between LFA-1 and ICAM-1 was found to significantly reduce the synthesis and secretion of autoantibodies and relieves cutaneous fibrosis in an experimental bleomycin-induced SSc model [ 14].

Blockage of this interaction dampens the response by inhibiting the nuclear translocation of NF-κB [ 42].

Further support for a role of TNFSF4 in atherosclerosis was obtained in a study where blockage of the TNFSF4/TNFRSF4 interaction reduced lesion formation in low-density lipoprotein (LDL) receptor-deficient mice [6].

Blockage of the CD40-CD154 interaction has been reported to alter cytokine production [ 16].

An effective blockage of this interaction could be important in anti-malarial vaccine design.

We hypothesize that blockage of these interactions through SAM contacts contributes to stabilization of the OFF state in the presence of ligand.

In contrast ceftazidime (Fig. 1d) and ampicillin (Fig. 1e) caused no significant blockage of the ionic current indicating negligible interaction with the channel.

Therefore in U87 cells pLG72 might enhance oxidative stress via the interaction of DAAO and blockage of the DAAO peroxisome targeting, resulting in producing H2O2 in cytosol and/or mitochondria.

Conceptually, treatment of DHS aims either to suppress the nerve impulse by direct neurological interaction or by mechanical blockage of the tubules.