Sentence examples for blockage of cell surface from inspiring English sources

Monoclonal antibodies can effectively recognize and kill cancer cells through different mechanisms such as direct stimulation or blockage of cell surface receptors, inhibition of tumor-related signal transduction leading to apoptosis, or indirectly through induction of host immune response.

Therefore, the functional blockage of the cell surface nucleolin represents a potential target for the development of anti-cancer therapeutics.

Altogether these results suggest that the downregulatory effect of doxorubicin on the surface expression of B7-H1 ispecificic and not due to apoptosis mediated membrane re-distribution of phospholipids or blockage of cell proliferation.

Activation of cell cycle checkpoints after DNA damages leads to the blockage of cell cycle progression.

Inappropriate expansion of hematopoietic progenitor cells is primarily caused by a blockage of cell maturation.

Our findings suggested that the normal NHERF1 function in mammary epithelial cells involves blockage of cell cycle progression.

Programmed death ligand 1 (PD-L1) is involved in the blockage of cell cycle in T-cells [ 31].

In plants exposed to Al, this mechanism activates blockage of cell cycle progression and thus root growth.

A number of therapeutic antibodies have been used for cell surface receptor blockage, interfering with the ligand binding and inhibiting receptor-driven activation of cells.

Dynamin led to the decrease of HER2 at the cell surface and this effect was partially blocked in cells expressing mutant huntingtin, suggesting that the mutant huntingtin blockage of HER2 internalization is dynamin-dependent.

The third target for specific blockage is inhibiting the pathway of AngII signaling by antagonizing AT1 which is the main cell surface receptor for AngII as well as blockage of AT2.