e Histogram of cell orientation θ at 10 days.
Activation of cell cycle checkpoints after DNA damages leads to the blockage of cell cycle progression.
Inappropriate expansion of hematopoietic progenitor cells is primarily caused by a blockage of cell maturation.
Our findings suggested that the normal NHERF1 function in mammary epithelial cells involves blockage of cell cycle progression.
Programmed death ligand 1 (PD-L1) is involved in the blockage of cell cycle in T-cells [ 31].
In plants exposed to Al, this mechanism activates blockage of cell cycle progression and thus root growth.
One of the molecular mechanisms by which antiestrogens inhibit cell proliferation is by decreasing CCND1 expression and blockage of cell cycle progression via the ER [ 32, 33].
This is of relevance, as direct blockage of cell cycle in OPCs would invariably result in cell differentiation (Dugas, Ibrahim, & Barres, 2007).
Blockage of cell cycle arrest can cause mitotic catastrophy, a form of cell death [ 13], whereas blocking of the anti-apoptotic transcription factor NF-κB promotes apoptosis [ 14].
Our data support another effect of DIMEB on grapevine cells: blockage of the cell-division process.
