Sentence examples for blockade of this effect from inspiring English sources

The blockade of this effect by coadministering a peripheral opioid receptor antagonist (naloxone methiodide), a nitric oxide synthase (NOS) inhibitor (L-NMMA), a soluble guanylyl cyclase inhibitor (ODQ), a PKG inhibitor KT-58233) or a K+ATP-channel blocker (glibenclamide) shows the involvement of a NO/cGMP/K+ATP-channel pathway.

Removal of Ca2+ did not affect the ability of morphine to increase pS133CREB or the blockade of this effect by NLX, NTX or VAKGL (Fig. 6).

Co-administration of cucurbitacin I (250 nm) produces a significant blockade of this effect (p <0.0005).

Co-administration of cucurbitacin I (250 nM) produces a significant blockade of this effect.

Therefore, the anxiolytic-like effect of the FAT-M and blockade of this effect by GABAA antagonists do not appear to be associated with nonspecific effects of the treatments on spontaneous locomotion.

Most importantly, both phenomena point toward the importance of the endogenous opioid system in pain modulation, as indicated by blockade of the effect in the presence of the opioid antagonist naloxone [3], [5], [6].

Blockade of the effects of ADP at either of these receptors results in a marked reduction in the overall effect of ADP on platelet function [ 2, 3].

These improvements were observed after 2 weeks to 6 months of treatment and are believed to be mediated through blockade of the effects of angiotensin II, the levels of which are elevated during exercise.

CCL21 also enhanced the proliferation of anti-immunoglobulin (Ig M-stimulated B cells and blockade of CCR7 Ig M-stimulatedeffect.

Only in HCT116-KD3b transfectants was colony formation also decreased by blockade of IIIb; however, this effect was transient, and 3 or more days after plating, no evidence of growth inhibition by the construct remained.

The incomplete blockade of metformin effect was likely due to residual AMPKα proteins (Fig 2D) and/or AMPK-independent mechanisms of metformin.