Sentence examples for blockade of the terminal from inspiring English sources

Blockade of the terminal complement pathway with eculizumab has been proved to be efficacious in aHUS [ 72– 72].

Given that these diseases are both mediated via the alternate complement pathway, it is tempting to speculate that blockade of the terminal complement pathway through the use of eculizumab might improve outcomes.

One should also keep in mind the ability to achieve long-term remission of neuralgic pains by means of neural blockades of the terminal trigeminal nerve branches using lidocaine or bupivacaine solutions.

We employed iAb blockade of the N-terminal 12-17 AA site to determine the importance of cleavage here in the degradative process.

Thus, high levels of the eukaryotic translation initiation factors produce a shift towards truncated C/EBP isoforms that, in turn, induce a blockade in the terminal differentiation of 3T3-L1 cells [30].

This latter could be the consequence of our failure to microsequence some of the protein bands because of poor recovery from the PVDF membrane or blockade of their NH2-terminal end (see the Additional file 2, Figure S2).

Therefore, de-activation of complex I would lead to the blockade of terminal electron transfer from N2 to ubiquinone due to a structural rearrangement of two crucial membrane subunits, ND1 and ND3.

Whole body cooling elicits reflex vasoconstriction through release of noradrenalin and cotransmitters from sympathetic nerve terminals; effective blockade of presynaptic nerve terminals abolishes the response, while at non-treated sites perfusion drops (Kellogg et al. 1989).

Blockade of C5, although potentially useful in minimizing complement effects during rejection, also prevents activation of the terminal complement cascade, theoretically decreasing MAC-mediated pathogen clearance induced by all pathways of complement (1).

Based on these observations and experimental evidence it has been suggested that blockade of terminal complement activation, of Fc-receptor-mediated, antibody-dependent cellular cytotoxicity or of the recruitment of neutrophils and eosinophils should be followed as therapeutic strategies in NMO patients with active disease [ 42, 47, 53].

The sinus nerve responses to H2S donors were prevented by blockade of the transmission between type I cells and the afferent terminals, as was the response to hypoxia.