Sentence examples for blockade of cell proliferation from inspiring English sources
In opposition, blockade of cell proliferation results in decreased food intake and body adiposity in these mutant mice but not in controls [19].
However, in silenced cells tamoxifen blockade of cell proliferation was not counteracted by KGF (10.5% versus 40.5%, 3.9 fold difference, P<0.001) Taken altogether, these results highlight the ability of siKGFR to prevent KGF from blocking the antiproliferative effect of tamoxifen in ER positive cells.
In addition, the blockade of cell proliferation by the EP1 antagonist revealed a possible contribution of EP1 signalling to PGE2 dependent HT-29 cell proliferation.
Previous studies demonstrated that p21 could act as a "tumor suppressor" by binding to cellular CDK and proliferating cell nuclear antigen (PCNA), thereby inhibiting their function and leading to cell cycle arrest, leading to blockade of DNA synthesis and inhibition of cell proliferation [ 15, 16].
Also, TN-mediated inhibition of cell proliferation has been markedly associated with blockade of cell cycle progression and consequent cell arrest in the G0/ G1 transition [ 58, 59, 164, 169].
Blockade or disruption of Clcn3 channel resulted in arrest of cell cycle and prevention of cell proliferation in several cell types [21], [50].
The specificity of the effect being due to AQP1 blockade was confirmed by transfecting both H226 cells and primary cells with AQP1 siRNA, which resulted in comparable decrease of cell proliferation compared to the controls.
Redox control of cell proliferation.
A study of cell proliferation.
Consistently with this hypothesis, EZH2 genetic of pharmacologic inhibition induces the blockade of eRMS cell proliferation and the appearance of a muscle-like phenotype [ 11].
Further evidence obtained from the immunohistochemical examination demonstrated that the tumor growth inhibition was closely correlated with the high rate of apoptosis among endothelial cells and the effective blockade of endothelial cell proliferation.
