Sentence examples for blockade of cell growth from inspiring English sources

The blockade of cell growth was accompanied by a change in their morphology with the appearance of cytoplasmic vacuoles (data not shown).

These results are concordant with the results of IS3 blockade inhibition of cell growth.

In a separate series of experiments to test the effects of AR blockade on cell growth, control and CAsE-PE cells were grown in steroid-depleted media for 48 hr then fed fresh steroid-depleted media with or without the antiandrogen flutamide (5μg/mL; Sigma) in the absense or presence of DHT (0.1μM).

A similar restoration of cell growth occurred after receptor blockade by JNJ7777120 (data not shown).

Our results now demonstrate that overexpression of FGFR3-IIIc stimulates tumour cell growth, whereas its blockade inhibits cell growth and induced apoptosis in colorectal cancer cells.

They found that blockade of VEGFR2 would abrogate the VEFG-mediated enhancement of astrocytoma cell growth and viability [ 37].

These data suggest that blockade of the expression of STAT3-drived cell growth and apoptosis-related genes may be involved in the inhibition of STAT3 decoy ODN on growth of human lung cancer cells in culture.

Sunitinib is a multitargeted TKI which results in VEGF signaling blockade to suppress cancer cell growth.

Both the cytotoxic and cytokinetic results revealed that the growth-inhibition by H-8 of P388 cells is mainly due to a blockade of cell-cycle progression rather than due to a killing of cells.

More recently, HER-3 phosphorylation in colorectal cancer cells was shown to be strictly dependent on association with HER-2, and that HER-2/HER-3 signalling reversed the effect of EGFR blockade on inhibiting colorectal cancer cell growth (Zhang et al, 2014).

Epidermal growth factor receptor-associated protein tyrosine kinase complexes also have vital antiapoptotic functions in human breast cancers (Modjtahedi et al, 1998; Witters et al, 1999) and the blockade of EGFR not only adversely affected cell growth, but also showed a sign of terminal differentiation and induces apoptosis in the human cancer cells (Modjtahedi et al, 1998).