Sentence examples for blockade may represent a from inspiring English sources

The first data on a likely anti-CD200 treatment in neoplastic diseases come from hematologic malignancies where it has been demonstrated that CD200 blockade may represent a novel approach to clinical treatment of CLL [ 79].

The results further support the hypothesis that IL1 blockade may represent a useful and selective treatment strategy for the growing population of patients with gout, including chronic, refractory gouty arthritis, suggesting that rilonacept should be studied further in patients with gout.

The interaction between CXCR1/2 and IL-8 increases CSC self-renewal; thus, CXCR1/2 blockade may represent another attractive target.

These findings demonstrate the importance of Ca2+-induced intracellular Ca2+ release in excitotoxic insult and suggest that blockade of glutamatergic overactivity may represent a therapeutic target in the treatment of METH withdrawal.

Hence, blockade of HER family/PI3K/Akt may represent a useful treatment modality for prostate cancer.

Thus, blockade of this pathway may represent a novel immunomodulatory strategy for the treatment of cancer.

In the current study, we investigated whether specific blockade of IL6 activities may represent a potential therapeutic to treat human DMD.

Treg cells migration into the tumor microenvironment is mediated by the CCL5/CCR5 axis in pancreatic adenocarcinoma, and blockade of this pathway may represent a novel immunomodulatory strategy for the treatment of cancer.

These findings give rise to the thesis that blockade of natriuretic peptide signalling may represent a novel therapeutic target that would prevent the (cardio vascular hyporeactivity that underlies the high mortality associated with this condition.

We propose that blockade of cytokine mediated trigeminal activation may represent a potential mechanism of action that mediates the preventive effect of MTP on cluster headache and recurrent migraine attacks.

Blockade of cytokine/receptor and chemokine/receptor signaling may represent a potential therapeutic target for inflammation-associated bladder dysfunction.