Figure 3 A shows a histogram of blockade depths (⟨ i⟩/⟨ i 0 ⟩), for the measured PEG sample.
Consequently in some cases depth of neuromuscular blockade could be considered as excessive by some physicians.
However, in the ACURASYS study (1), cisatracurium was administered at a constant and high posology without monitoring the depth of neuromuscular blockade.
Depth of neuromuscular blockade was assessed using the TOF Watch™ SX (Organon Medical Systems, Roseland, NJ, USA), which monitors neuromuscular transmission during surgery or intensive care by means of acceleromyography.
Failures to comply with management or diagnostic guidelines (for example, review of chest x-ray after line insertion or no monitoring of depth of neuromuscular blockade in patients receiving neuromuscular blocking agents) were summarized under the heading of poor practice.
Monitoring the depth of a neuromuscular blockade with peripheral nerve stimulation (PNS) is recommended only in combination with a clinical assessment by critical care societies [2, 4, 5].
As it is already known in the operating room setting [10, 11], our study shows that an overall clinical assessment of the depth of a neuromuscular blockade is not correlated with the TOF count in critically ill patients.
Supported by several cruisers, the ship then blockaded Dakar and attempted to sink the by exploding depth charges underneath her stern, as well as sending Fairey Swordfish torpedo bombers to attack her at night.
These developments will be discussed, and then recent research in control of depth of anesthesia, as well as in analgesia, neuromuscular blockade will be reviewed.
The depth of sedation may have influenced the clinical evaluation of the neuromuscular blockade.
