Your English writing platform
Discover LudwigExact(2)
To verify the efficiency and applicability of the proposed method, it is applied to block turnover simulation.
We co-transfected HeLa cells with control siRNA or siRNA directed against ATG16L1 and either empty vector or ATG16L1 variants, followed by treatment with ammonium chloride to block turnover of the autophagy marker LC3 in autolysosomes.
Similar(58)
Blocking MVB turnover enhanced, whereas blocking MVB maturation inhibited miRNA-mediated target mRNA silencing, indicating that MVBs and GW bodies are functionally involved in miRNA-mediated RNA silencing.
Joseph Linklater, a lawyer for Mr. Davidge, moved unsuccessfully to block the turnover of Mr. Davidge's material as a possible risk to his Fifth Amendment privilege against self-incrimination.
However, uev-1 mutations partially block the turnover of GLR-1 caused by increased ubiquitin levels (Figure 8D,G), suggesting that UEV-1 is required for one or more ubiquitin-mediated processes that regulate GLR-1 trafficking.
To discern between these two possibilities, we examined LC3B accumulation following treatment with the lysosomotropic agent, chloroquine, to block autophagosome turnover.
To block the turnover of norepinephrine aldehydes, perhaps one might self-administer ethanol to compete DHPG and HMPG, because ethanol is an external competitor for internal DHPG and HMPG on π ADH [ 37].
Blocking oil turnover processes might help increase the level of oil accumulated, as was observed in Arabidopsis leaves where the oil content was increased tenfold by knocking out a lipase gene [126].
Thus, knockdown of either PI4K isozyme blocks PI 4,5 P2 turnover without any inhibition of EGF-stimulated phosphorylationlation.
This renders pH-dependent lysosomal hydrolases and proteases nonfunctional, blocks lysosomal turnover, and inhibits the final completion stage of autophagy.
Trx reduces protein SNOs directly, and inhibition of thioredoxin reductase (TrxR) can increase protein SNOs by blocking Trx turnover.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com