Sentence examples for block the interaction of from inspiring English sources
Multivalent ligands that exhibit high binding affinity to influenza hemagglutinin (HA) trimer can block the interaction of HA with its sialic acid receptor.
To better understand how various inhibitors might block the interaction of VCAM and fibronectin with α4β1, we began constructing a structure model for the integrin α4β1 complex.
Thus the CDK1 inhibitor roscovitine and an antibody we designed to block the interaction of CDK1/cyclin B1 with separase, both failed to induce sister disjunction.
Notably, TNFR1 blocking peptide-Fc fusion protein was shown to block the interaction of PGRN with TNFR1 and resulted in the restoration of insulin sensitivity, showing a significant relationship between PGRN and TNFR1 (Li et al., 2015; Liu et al., 2015).
However, in our current study, although we have observed the interaction of RNF43 with β-TRCP with comparable level as ZNRF3 (Fig. S1C), the interaction of RNF43 was not impaired by F-box mutation of β-TRCP (S474A) (Fig. S1D), furthermore, the potential degron deletion could not block the interaction of RNF43 with β-TRCP (Fig. S3).
Recent advances in the structural and binding chemistry of these cytokines various types of inhibitors were designed to block the interaction of IL-4 and IL-13 with their receptor, including several IL-4 mutant analogs and IL-4 antagonistic antibodies.
By interacting with Beclin-1, Bcl-2 blocks the interaction of Beclin-1 with PI3KIII, decreases PI3KIII activity, and down-regulates autophagy.
Basiliximab binding can completely block the interactions of IL-2 with IL-2Rα [2].
The potential of recombinant ALP to block the interactions of leukocytes with the endothelial lining was concomitantly investigated in vitro and in vivo.
In conclusion, AMD3465 is a novel, monomacrocyclic anti-HIV agent that specifically blocks the interaction of HIV gp120 with CXCR4.
