Sentence examples for block the interaction from inspiring English sources

Synthetic compounds mimicking such tetrapeptide motif effectively block the interaction between IAP and active caspases, thus triggering apoptosis.

Accordingly, several PD-1/PD-L1 blockers have been designed to block the interaction between PD-1 and PD-L1 to enable anti-tumour immunity.

Several chemicals, such as Nutlin and MI-219, have been developed to block the interaction between Mdm2 and p53 (Shangary et al., 2008; Vassilev et al., 2004).

Rationally designed CD80 and CD154-binding peptides block the interaction between cell surface costimulatory molecules on antigen-presenting cells (APCs) and T cells.

Multivalent ligands that exhibit high binding affinity to influenza hemagglutinin (HA) trimer can block the interaction of HA with its sialic acid receptor.

To better understand how various inhibitors might block the interaction of VCAM and fibronectin with α4β1, we began constructing a structure model for the integrin α4β1 complex.

It is very important to explore the interaction between S100B and p53 and to develop inhibitors to block the interaction in anti-cancer development.

The BCL-2 family binders block the interaction with their natural interaction partner and will be valuable reagents to test the apoptotic response in functional assays.

Thus the CDK1 inhibitor roscovitine and an antibody we designed to block the interaction of CDK1/cyclin B1 with separase, both failed to induce sister disjunction.

Knowledge of structure and function of this system has allowed the development of inhibitors that block the interaction between the cytokines and their shared receptor.

Interestingly, small-molecule inhibitors that block the interaction between the MED15-KIX domain and the transactivation domain of SREBP-1a protect mice from the metabolic dysregulation that occurs during diet-induced obesity (Zhao et al. 2014).