Sentence examples for block the initiation of from inspiring English sources

EGFR inhibitors block the initiation of the pathway at the upstream receptor site while MEK/Raf inhibitors block pathway signaling at one of the effector sites downstream from the receptor.

For example, the methylation surrounding TSS will block the initiation of transcription, while the methylation in the gene body will not block the transcription but even sometimes stimulate it (Suzuki and Bird 2008).

Furthermore, morpholino antisense oligos (MOs) have been widely used in zebrafish to block the initiation of translation, and this method has proved to be highly reliable [11], [12].

Alltogether, these results showed that depending on the concentration used, a microtubule-disrupting drug can either inhibits centriole elongation or block the initiation of centriole growth.

The decrease in non-motile cells over time indicates that cells initially scored as non-motile can initiate movement showing that non-motile cells are not dying and that lack of FLNs does not completely block the initiation of migration.

Some studies indicate that miRNAs block the initiation of translation, in some instances triggering the formation of large ribonucleoprotein (RNP) 'pseudo-polysomes', yet others suggest that miRNAs suppress post-initiation steps by repressing translational elongation, by promoting ribosome drop-off or by inhibiting termination [23] [26].

In The Reagan Imprint, he laments that Reagan's secretary of defense, Caspar Weinberger, blocked the initiation of a "war on terror" that the president had approved in a still-classified 1984 document, National Security Decision Directive No. 138.

Defense Secretary Robert M. Gates is expected to soon lift an order blocking the initiation of new cases against detainees, which he imposed on the day of President Obama's inauguration.

For example, DNA methylation at gene promoter CGIs potently blocks the initiation of transcription, whereas methylation within CpG-poor gene bodies may actually facilitate elongation and influence patterns of alternate splicing.

Although many antibiotics work this way, the exact mechanism of action of linezolid appears to be unique in that it blocks the initiation of protein production, and not one of the later steps.

The overexpression of Myc6-Sgo1 blocked the initiation of AII and kept the oocytes at MII.