Sentence examples for block the fusion between from inspiring English sources

Nevertheless, it can also block the fusion between autophagosomes and lysosomes, leading to accumulation of autophagosomes.

TSV-LAO was unable to block the fusion between HIV-1 and host cells, suggesting that this enzyme does not interfere with the absorption and/or binding of the virus to the host cell.

Vacuolin-1 treatment also blocked the fusion between endosomes and lysosomes, resulting in a defect in general endosomal-lysosomal degradation.

We have recently shown that silymarin and other synthetic antivirals block the fusion process [11], [30].

Manzamine A could block the fusion of autophagosome and lysosome and abrogate autophagosome turnover [ 13].

As a vacuolar-type H+-ATPase inhibitor, bafilomycin A1 blocks the fusion between autophagosomes and lysosomes and thus the degradation of LC3II [44], [44].

Taken together, these data clearly demonstrated that vacuolin-1, similar to BAF or CQ, blocks the fusion between autophagosomes and autolysosomes, thereby leading to accumulation of LC3B-II positive autophagosomes.

To test the possible connection between the post-fusion [Ca2+]c increase and the actin coating we tried to block the post-fusion [Ca2+]c increase with the unspecific Ca2+ channel blocker SKF96365.

The anti-HIV drug maraviroc binds the virus coreceptor CCR5 [ 30], while enfuvirtide is able to block the viral protein GP41, reducing the fusion between viral and cellular membranes [ 31].

The PI-induced inhibition was apparently a consequence of a block at the level of the fusion between viral envelope and endosomal membranes.

These viruses likely block the fusion of autophagosomes that carry the viral replication complexes with lysosomes.