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In addition, functionalized nanoparticles themselves or their metabolites can also block the function of ABC transporters such as P-gp by direct or indirect interaction and inhibition.
Indeed, drugs that specifically block the function of the mutated EZH2 protein are in development.
Researchers gave each monkey a local anesthetic to temporarily block the function of the flexor nerves in its arm.
Stimulated secreted Noggin protein failed to block the function of BMP-2 in the presence of 26SCS.
As a countermeasure, numerous phages are known that produce proteins to block the function of class 1 CRISPR-Cas systems.
Monoclonal antibodies are traditionally used to block the function of a specific target in a given disease.
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Antibodies that simultaneously block the functions of two or more disease-associated targets are now being developed.
Recently a new concept is emerging to develop BsAb that simultaneously block the functions of two tumor-associated targets, eg., growth factor receptors, for enhanced antitumor efficacies.
These experiments were performed in the presence of irreversible inhibitor of cysteine peptidases, N-ethylmaleimide (NEM), to block the functions of ubiquitination and de-ubiquitination.
These proteins form a stable TA complex to block the functions of the Doc toxin.
To confirm the association of Gal-3 expression with resistance to cisplatin, GCS-100/MCP was used to block the functions of Gal-3.
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