Sentence examples for block the binding between from inspiring English sources

ADA ultimately act by causing the formation of complexes that block the binding between the drug and the target and also enhance the drug's clearance [78].

In this study, we tested the feasibility of inhibiting activation of proMMP-2 by exogenous inhibitors, which block the binding between PEX and TIMP-2.

IRNA could thus block the binding between GlLa and GLV-IRES in vitro.

We have selected the small molecules PKF115-584, PKF118-310 and CGP049090, which block the binding of β-catenin to its transcription factor TCF4. PKF115-584 and CGP049090 also block the binding between β-catenin and transcription factor Lef1 [ 22- 24].

In the competition assays, peptide number 3 and 4 completely blocked the binding between Sjc23-LED and human IgG (Fig. 6A and B), but not the other peptides.

Blocking the binding between UPIa of umbrella cells and FimH of bacteria is an ideal target for infectious cystitis treatment.

Furthermore, we were able to confirm that omalizumab specifically blocked the binding between IgE and FcεRI (Figs 2b, 3b).

Therefore it is possible that the RC-1, which is a cationic peptide, may inhibit the activity of dengue protease via direct interactions with the active site or by blocking the binding between the two subunits of the protease complex.

Blocking HSP90 clearly increased the binding between HSP70 and HIF-1α (Figure 4A).

In addition, PKF115-584 nonlynly blocks but also disrupts the binding between β-catenin and TCF [ 22- 24].

Taken together, our data and these previous reports could suggest that Thr46 phosphorylation is sufficient to block the initial binding between eIF4E and 4E-BP1 as observed by far western analyses, but that hyperphosphorylation of 4E-BP1, including at Ser65, is required to disrupt existing 4E-BP1 eIF4E complexes.