Sentence examples for block the assembly of from inspiring English sources

Amantadine can also block the assembly of influenza virus during viral replication.

Ansamitocins, produced by Actinosynnema pretiosum, are a group of maytansinoid antibiotics that block the assembly of tubulin into functional microtubules.

Disruption of CA CA contacts by small molecules could block the assembly of immature particles or of the mature capsid core.

We show that mutations in the metazoan branchpoint sequence (BPS) have no apparent effect on E complex formation but block the assembly of the A complex and the UV cross-linking of U2 small nuclear ribonucleoprotein particle (snRNP) proteins.

Its primary cellular function seems to be the inhibition of the viral life cycle as it can block the assembly of multiple viruses27 including the vesicular stomatitis virus28, and prevent the nuclear entry of HIV29.

The ability of p16INK4a to inhibit the cyclin D-dependent kinases also enables it to block the assembly of DNA replication complexes onto chromatin and thus inhibit DNA replication, a function not shared by p21Waf1 [ 50].

PLpro-TM disrupts activation of the IRF3 pathway induced by STING-TRAF3-TBK1 blockinging the assembly of the complex, and it deubiquitinates the signaling molecules RIG-I, TRAF3, STING, TBK1, and IRF3.

On the other hand, mTORC2 only responds to prolonged and chronic rapamycin treatment, in part because rapamycin cannot directly interfere with existing mTORC2 complex, but rather only blocks the assembly of mTORC2 from newly synthesized Rictor and mTOR (Sarbassov et al., 2006).

Both scFV were incapable of blocking the assembly of VLP, or be copackaged with Pr55Gag into VLP.

Neither dominant-negative variants nor peptide inhibitors of Rho GTPases blocked the assembly of the cytoplasmic actin network.

Binding between 4E-BP1 and eIF-4E blocks the assembly of the eIF-4F protein translation initiation complex.