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Soluble carbohydrates recognized by the bacterial surface lectins block the adhesion of the bacteria to animal cells in vitro.
The competition between nano-topography and a controlled dosage of drugs may either accelerate or block the adhesion of cells on a nanostructured surface, for applications in tissue engineering, regenerative medicine, personalized lab-on-a-chips, and the rational design of implantable drug delivery systems.
The contact angle variation after the surface soaked in protein solution indicates that the fabricated biomimetic surface microstructure can block the adhesion of protein.
Ideally, a vaccine against PM will induce antibody-mediated immune responses that block the adhesion of infected erythrocytes (IE) in the placenta.
Kobayashi et al (2000) showed that cimetidine can block the adhesion of colorectal cancer cells to the endothelial cells, suppressing the metastases of cancer cells.
However, the addition of specific peptides that block the adhesion of E-cadherin and desmocollins (desmosomal cadherins) resulted in disturbances in polarity, and the structures in Matrigel or the double-layered tubes in solution failed to organize.
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We found that compound 8a significantly blocks the adhesion of neutrophils to endothelial monolayer.
Jerdostatin selectively blocked the adhesion of α1β1-K562 cell to collagens I and IV in vitro and angiogenesis in vivo.
MAb 107 is a ligand mimic of CR3 that blocks the adhesion of leukocyte and their transendothelial migration (diapedesis), a feature that confers this MAb a potential anti inflammatory activity.
It has been shown that EGCG binds to the intercellular adhesion molecule 1 (ICAM 1) on the endothelium thus blocking the adhesion of Plasmodium infected erythrocytes [20].
To our knowledge, however, our report is the first to show that LL-37 blocks the adhesion of a fungal pathogen to substrates.
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