Sentence examples for block randomisation will be from inspiring English sources
A block randomisation will be used, allowing eight participants at a time to be randomised in equal proportions for S-ketamine or matching placebo.
Block randomisation will be dominant over minimisation.
To ensure balanced groups, block randomisation will be used.
Block randomisation will be used to ensure equity of ample sizes across study conditions.
Computerised block randomisation will be used to allocate participants to groups.
Block randomisation will be used with three varying block sizes of minimum size 4.
Stratified permuted-block randomisation will be performed using R statistical software to achieve balanced allocation of participants within study site and within strata of birth weight (≥ or <1500 g).
To make sure that two equal groups of 18 subjects will be obtained, blocked randomisation will be used (block size of 6).
To achieve balance between the treatment arms during the trial, blocked randomisation will be used with random sequences of different block sizes.
Blocked randomisation will be carried out by the research team, using a computer-generated sequence to ensure an almost equal number of patients within each group.
