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"Our findings suggest potential strategies for using normal gut bacteria to block progression of insulin-dependent diabetes in kids who have high genetic risk," Dr. Danska added.
One approach towards overcoming these limitations is to block progression of the viral replication cycle at an earlier stage than normally occurs with MVA infection.
These structures can potentially block progression of the replication fork and cause intra- or inter-molecular template switching of DNA polymerase between the inverted elements [15], [19].
Exposure to the carrier, DMSO, from 1 hr onward did not block progression of MK cells into S-phase (Fig. 1B, right side).
Thus, the tyrosine kinase inhibitors may block progression through S-phase without inducing apoptosis.
67– 70 Unrepaired lesions (particularly bulky adducts, intercalations, crosslinks, and helix distortions) can block progression of the replication fork.
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It is suggested that downregulatory immune mechanisms, which dampen the anti-parasite response, might benefit the host by blocking progression to atopic reactions.
Thus, gp130 in hepatocytes seems an interesting therapeutic target for blocking progression of HCC.
p21 blocks progression of the cell cycle at G1/S and is involved in G2/M phase arrest (Dulic et al, 1998).
This indicates that cdc6-E224Q blocks progression into S-phase as expected for a defect in DNA replication initiation.
63 In K5.hTGF-β1 transgenic mice, presenting a skin phenotype and cytokine alterations analogous to those found in psoriasis, administration of anti-IL-17A blocked progression of disease.
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