Sentence examples for block of cell differentiation from inspiring English sources

First, the Dp53-induced block of cell differentiation which is independent of hid, is suppressed by p21.

39 We extend these observations further and show here that human p21 not only suppresses Dp53-induced apoptosis, but also suppresses the Dp53-induced block of cell differentiation.

An Hh-signal-specific inhibitor, cyclopamine, induces growth inhibition in Hh-activating GC cells; meanwhile in normal gastric epithelium, cyclopamine causes a block of pit cell differentiation followed by epithelial hyperplasia (Fukaya et al, 2006).

This finding highlights a common final outcome of the block of MK cells differentiation in both DS and non-DS AMKL.

41, 42 Decreased E-cadherin expression through the inhibition of CLCA1 might block cell differentiation and increase the likelihood of distant metastasis.

Recently, we have shown that ONX 0914 blocked Th17 cell differentiation of T cells cultured in the presence of polarizing cytokines (Muchamuel et al, 2009).

Stabilization of β-catenin blocks Clara cell differentiation to ciliated cells and increases the number of naphthalene-resistant progenitor cells.

We reasoned that a block in prestalk cell differentiation would create a block at the aggregative stage with the absence of tip formation, as observed.

Summing up, downregulation of the CSN led to a block of LiSa-2 cell differentiation.

The c-Myb transcription factor is responsible for the proper regulation of hematopoiesis [8] and inhibition or ablation of c-myb gene expression blocks hematopoietic cell differentiation in vitro [9] and leads to a loss of hematopoietic cells in animals [10].

Our analysis indicates that Dp53 blocks cell differentiation of photoreceptor neurons and cone cells independently of its pro-apoptotic role.